Side effects of Methadone

3 min read
30 November 2022


Methadone is an opioid used to treat pain and addiction. It is also prescribed for people who are recovering from surgery or other medical procedures that cause discomfort. The drug has many side effects, but some of them may be more serious than others.


Constipation is a common side effect of methadone. The reasons for constipation are very similar to those of the other opioid drugs, although they are a bit more specific.Use methadone check for methadone clinic near you. 

Methadone can slow down your digestive system and make it hard to pass stools, or even cause you not to pass any at all. This is especially true if you have taken other medications that affect your intestines before taking methadone (or if you have been taking opiates for a long time). In some cases, this can lead to severe constipation symptoms such as:

  • pain when passing stools
  • bloating after passing stools


You may feel dizzy or lightheaded when you take methadone. As a result, it's important to know the symptoms of this condition and how to prevent them from happening again.

Dizziness can be caused by a drop in blood pressure. It is also possible that your body is getting used to the medication and you are no longer experiencing as much dizziness as before taking methadone (that's why it may take a few weeks before any changes occur).


Headaches are a common side effect of methadone. Most headaches are mild and go away on their own, but if you develop a severe headache or one that doesn't go away, talk to your doctor. If you develop a fever while taking methadone, contact your doctor immediately.


Irritability is a common side effect of methadone. It can occur when you first start taking methadone or in response to changes in your medication, such as dosage adjustments or switching brands.

Irritability may be a sign that you're experiencing withdrawal symptoms—if so, talk to your doctor about how best to manage them. You might also consider speaking with someone who's experienced addiction before if this sounds like something that could help:

  • A friend or family member who's been through it themselves (or someone they know)
  • A professional therapist


Methadone is a narcotic that has a strong sedative effect. The use of methadone can cause drowsiness, which may be problematic for people who drive or operate heavy machinery. Some patients experience lethargy with their medication as well.

increased sweating

You may notice that you sweat more than usual when you take methadone. This is a common side effect of the drug and can be caused by several factors, including:

  • The amount of methadone in your system
  • Your fitness level
  • Your mental state

It can cause symptoms such as lethargy and dizziness.

Methadone can cause symptoms such as lethargy and dizziness. You may also feel nauseous, or have constipation or drowsiness. You may have a headache, sweating, or feeling of being drunk while taking methadone. Learn more about suboxone and methadone.


The common side effects of methadone include drowsiness, dizziness, headaches, and constipation. These are usually mild and can be treated with over-the-counter medications or with prescription drugs if they become more severe.

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Kelly Bliss 2
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