Which Zinc Sulphate is Best For You?
Among the numerous treatments available for ulcers and wounds of various etiology, zinc sulphate is one of the most effective. Besides, it is also known to be an excellent topical treatment for psoriasis and herpes genitalis. It can also be used as an aid in the treatment of diabetes.
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Treatment for pityriasis versicolor
Using zinc sulphate as a treatment for pityriasis versicolor is a relatively new therapeutic approach. The benefits of this approach include reduced recurrence rates, increased safety profile, and improved therapeutic outcome. The effectiveness of this treatment has been evaluated in several studies.
A double blind crossover study was conducted to evaluate the effectiveness of zinc sulphate against placebo. Thirty patients with pityriasis versicolor were recruited and treated. Each patient underwent a full history and physical examination. Each patient was given a description of the diagnosis and the potential side effects of the treatment. The patients were then asked to consent to the treatment. The subjects were then observed every two weeks. The MASI score was also evaluated.
The study results showed that the MASI score was significantly lower in the zinc sulphate and zinc sulphate heptahydrate group than in the control group. Additionally, the treatment was associated with a reduction in recurrences in the recurrent aphthae.
Treatment for herpes genitalis
Several studies have investigated the use of zinc sulfate for herpes genitalis. These studies have yielded conflicting results. Early research focused on the use of zinc in combination treatments. This was followed by more in-depth studies on the use of topical zinc sulfate and its effect on the immune system.
Zinc salts inactivate HSV clinical isolates in vitro. However, the extent of inactivation is dependent on the type of HSV, the concentration of zinc used, and the length of treatment.
In preliminary experiments, a number of strains of HSV were efficiently inactivated in the presence of 15 to 50 mM zinc salts. Some of these findings were similar to the effects of zinc gluconate or zinc lactate. These compounds were effective in inactivating HSV-1 and HSV-2 isolates. In one study, the inactivation of HSV-1 was almost complete when it was treated with zinc gluconate at 50 mM.
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Treatment for psoriasis
Several studies have been conducted on the topical application of zinc sulphate for psoriasis. However, more studies are required before the therapy is recommended.
The therapeutic action of zinc is based on its anti-inflammatory, healing and antineoplastic properties. Zinc has been used in a variety of inflammatory dermatoses such as eczema, diaper dermatitis, pityriasis, acne and warts. These disorders are characterized by symmetric, hyperpigmented patches of skin.
In a study of topical treatment of pityriasis versicolor, topical 15% zinc sulphate solution was found to be effective. It was also found to be useful in pityriasis of the foot and in bromhidrosis. The only side effect of the treatment was a mild burning sensation at the site treated. It was noted that, unlike the steroid, the sulphate solution was safe and had no toxicity.
Treatment for ulcers and wounds of varied etiology
Several studies have suggested that platelets and zinc play an important role like L-Glutathione in wound healing. However, there is still limited information regarding the clinical benefits of zinc in these disorders. Identifying the role of zinc in these conditions will help to advance the development of wound healing treatments.
Zinc is an essential trace element in the body. It plays a role in immune homeostasis and reproductive functions. It also has antioxidant properties. In high concentrations, zinc has a direct cytotoxic effect, inducing apoptosis of malignant cells. The benefits of zinc are believed to be related to its ability to modulate adaptive and innate immune functions.
Zinc deficiency can impair the function of macrophages. M1 macrophages are important for early inflammation, microbial clearance and tissue remodelling. M2 macrophages are associated with immunity suppression and tissue repair.
Treatment for diabetes
Several studies have shown that Zinc sulphate can be a beneficial treatment for diabetes. The main effect of Zinc on the disease is the ability to delay micro- and macro-vascular complications.
Zinc is a critical element in glucose metabolism, enzyme action, ammonium sulphate, gene expression, and cell membrane stabilization. It is also important in the synthesis of insulin. Research has shown that Zinc supplementation in patients with type 2 diabetes improves their glycemic control. This is because it reduces triglycerides, LDL cholesterol, and HbA1c. It also has a protective effect against diabetes-induced peripheral nerve damage.
In diabetes, inflammation plays a critical role. This is a result of the increased production of ROS, which are responsible for activating five major pathways involved in the complications of diabetes. A recent meta-analysis concluded that Zinc supplementation improved glycemic control in diabetic patients.
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