chemistry
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World of Amorphous Crystals: A Delicate Balance Between Order and Disorder
In the realm of materials science, crystals have long been celebrated for their pristine order and symmetry. Yet, amidst the world of perfectly structured crystalline solids lies an intriguing anomaly – amorphous crystals. These materials, sometimes referred to as "amorphous solids" or "glasses," defy the conventional definition of crystals w...
Ron Chemists · 28 August · 4Drug-to-Antibody Ratio Analysis Methods
Average drug-to-antibody ratio (DAR) and drug load distribution are two vital properties of antibody drug conjugates (ADCs). Over the years, several ADC bioanalytical methods have been developed to better estimate these properties...
Krystal Beily · 04 August · 3
A Brief Guide to Pichia pastoris Fermentation
What is pichia pastoris and its functions? Pichia pastoris is a type of yeast that is commonly used in biotechnology for the production of recombinant proteins. It is known for its ability to efficiently produce heterologous proteins with high yields. Pichia pastoris offers several advantages for protein production: Strong and...
Krystal Beily · 04 August · 1The Notable Breakthroughs in Drug Discovery with SILAC Technique
Stable Isotope Labeling by Amino Acids in Cell Culture (SILAC) is a powerful technique that allows for the quantification and characterization of proteins in cells and organisms. It involves the substitution of specific amino acids with their isotopically labeled counterparts in cell culture media. This labeling enables researchers to track and com...
Krystal Beily · 04 August · 3How to Find the Right Partner for Custom Chemical Synthesis
What can CROs do in custom synthesis? Process development and optimization: CROs can work with clients to develop and optimize synthetic routes for the production of target compounds. They can design and scale-up synthetic processes to efficiently produce desired molecules. Medicinal chemistry: CROs can support medicinal chemistry programs b...
Krystal Beily · 04 August · 4Effects of Endocytosis on the Receptor Targeting Mechanism of ADC Drugs
ADC is a complex that conjugates cytotoxic small molecule drugs to monoclonal antibodies through a rationally constructed linker, which can selectively deliver effective cytotoxic drugs into tumors. Currently, the FDA has approved 14 ADC drugs for marketing, and hundreds more are in clinical trials. In addition to overexpression in tumors, another...
Hugh Mono · 21 July · 7Unraveling the Secrets of Line Defects in Solids
In the intricate world of materials science, line defects in solids play a pivotal role in shaping the properties and behavior of various materials. These imperfections within the crystal lattice structure extend along specific lines, giving rise to intriguing phenomena and influencing crucial aspects such as mechanical strength, electrical conduct...
Ron Chemists · 13 July · 1Chemistry Jokes The Funniest You’ll Ever Hear
Chemistry jokes and chemistry pick up lines reddit are a great way to show your understanding of the subject, while also injecting a little levity into the classroom or workplace. And, like all jokes, they're even funnier when you know the punchline....
Ahmad saad · 19 January · 31
How to make the most out of your JC Chemistry tuition?
Chemistry is a fascinating topic, but it is not for the faint of heart. The idea that chemistry is difficult persists in the minds of some students, leading to apprehension about the topic. In a country where chemistry is revered, Singapore incorpor...
Global Education Hub · 07 June 2022 · 31